Today's emphasis is on cancellations of the past decade. Let's look for inspiration from these unfinished projects.
During their ongoing demise prior to 2013, THQ began developing an Avengers game for the PS3 and X360 to coincide with the Marvel movie released the same year. The studio responsible was THQ Australia, with some aid from Blue Tongue Enertainment. They planned on making a game that focused on controlling the team's members in a first-person perspective, using a story distinct from the film's. There would also be a strong element of cooperative play, with the campaign supporting up to four players online and locally.
The game was eventually cancelled in 2011 with the closure of both studios, but a fair amount of footage for the game exists. THQ would go out of business soon afterwards. However, the THQ of Ohga Shrugs has avoided this fate. Although there have not been many games of note tying into the Marvel Cinematic Universe since 2011's Thor and Captain America releases, a successful Avengers title could give THQ a chance to lead the Marvel brand in video games. This could include handheld and console games that tie into Iron Man 3, Guardians of the Galaxy, Age of Ultron, and so on. This might be worth looking into.
The Lord of the Rings: The White Council
EA Redwood Shores, later renamed Visceral Games, was working on this Lord of the Rings RPG in 2006 and 2007 for the PC, X360, and PS3. It was meant to take place in an open world, set in Middle-Earth some years prior to The Hobbit, and use the same AI technology as in The Sims 2. The ultimate goal would be to join the titular White Council. Though the game was set for a late 2007 release, it was cancelled due to unexplained management reasons.
Visceral Games had previously created a couple of Lord of the Rings games. One, 2004's The Third Age, was a decently received RPG with gameplay inspired by Final Fantasy X. Had The White Council been release in 2007, it would have shared the 7th generation consoles with few other RPG's of note. As it is, Visceral has been focusing on Dead Space and Battlefield instead.
Insane - THQ, Volition, Horror Earthqorm Jim PSP Highlander - Eidos Pirates of the Caribbean: Armada of the Damned - Disney